Laws and Penalties: Concerns over growing illegal AAS abuse by teenagers, and many of the just discussed long-term effects, led Congress in 1991 to place the whole AAS class of drugs into Schedule III of the Controlled Substances Act (CSA). Under this legislation, AAS are defined as any drug or hormonal substance, chemically and pharmacologically related to T (other than estrogens, progestins, and corticosteroids) that promotes muscle growth. The possession or sale of AAS without a valid prescription is illegal. Since 1991, simple possession of illegally obtained AAS carry a maximum penalty of one year in prison and a minimum $1,000 fine if this is an individual’s first drug offense. The maximum penalty for trafficking (selling or possessing enough to be suspected of selling) is five years in prison and a fine of $250,000 if this is the individual’s first felony drug offense. If this is the second felony drug offense, the maximum period of imprisonment and the maximum fine both double. While the above listed penalties are for federal offenses, individual states have also implemented fines and penalties for illegal use of AAS. State executive offices have also recognized the seriousness of AAS abuse and other drugs of abuse in schools. For example, the State of Virginia enacted a law that will allow student drug testing as a legitimate school drug prevention program (48, 49).
Primobolan dosage and administration depends heavily upon which form is being used: oral or injectable. Medical prescription Primobolan dosages outline 200mg as a first dosage, followed with 100mg every week for the complete duration of therapy. The medical condition being treated would determine what the actual full Primobolan dosage is. The range can be anywhere from 100mg every one or two weeks to 200mg every two to three weeks. Medical guidelines for oral Primobolan dosages call for 100 – 150mg per day for no longer than 6 – 8 weeks of consistent use.
Pharmacokinetics. The absorption is independent of food intake. The bioavailability of escitalopram is approximately 80%. The mean time to maximum plasma concentration buy anavar 4 hours after repeated use. The apparent volume of distribution after oral administration is from 12 to 26 l / kg. The binding of escitalopram and its main metabolites in the plasma proteins below 80%. Escitalopram is metabolised in the liver to the demethylated and didemetilirovannogo metabolites. Both are pharmacologically active. Main ingredient and its metabolites in the form of partially allocated glucuronides.