A subpopulation of patients with asthma may have aspirin-sensitive asthma which may include chronic rhinosinusitis complicated by nasal polyps ; severe, potentially fatal bronchospasm; and/or intolerance to aspirin and other NSAIDs. Because cross-reactivity between aspirin and other NSAIDs has been reported in such aspirin-sensitive patients, CELEBREX is contraindicated in patients with this form of aspirin sensitivity [see CONTRAINDICATIONS ]. When CELEBREX is used in patients with preexisting asthma (without known aspirin sensitivity), monitor patients for changes in the signs and symptoms of asthma.
Based on the mechanism of action, the use of prostaglandin-mediated NSAIDs, including Celebrex, may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Published animal studies have shown that administration of prostaglandin synthesis inhibitors has the potential to disrupt prostaglandin mediated follicular rupture required for ovulation. Small studies in women treated with NSAIDs have also shown a reversible delay in ovulation. Consider withdrawal of NSAIDs, including Celebrex, in women who have difficulties conceiving or who are undergoing investigation of infertility.
Facial Additions A variety of optional enhancements are available that may be added to any of our facials, for you to look and feel even more beautiful. Select from French zip waxing for brow or lip, or choose one of the following options:
Wow Brow – Brows are lifted with NuFace microcurrent technology, opening the eyes for a wide-eyed youthful look. Results are instant and uplifting.
Lip Definer – Add volume to the lips with NuFace microcurrent technology, lifting and sculpting the jaw line and reducing the appearance of smile lines. Results are instant and uplifting.