Oxandrolone biotech

Although the mechanism of action of valproate is not fully understood, [48] traditionally, its anticonvulsant effect has been attributed to the blockade of voltage-gated sodium channels and increased brain levels of gamma-aminobutyric acid (GABA). [48] The GABAergic effect is also believed to contribute towards the anti-manic properties of valproate. [48] In animals, sodium valproate raises cerebral and cerebellar levels of the inhibitory synaptic neurotransmitter, GABA, possibly by inhibiting GABA degradative enzymes, such as GABA transaminase , succinate-semialdehyde dehydrogenase and by inhibiting the re-uptake of GABA by neuronal cells. [48]

Oxandrolone biotech

oxandrolone biotech

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