As Anadrol is considered by many to be the strongest oral anabolic steroid widely available, users can expect to gain some incredibly dramatic amounts of mass and strength on even the lowest Anadrol doses. It is not uncommon for beginners, for example, to add 20 – 30 lbs. of mass on a bulk within only several weeks of use. Of course, much of this weight can be attributed to the water weight retained as a result of the Estrogenic effects of Anadrol . Because Anadrol is commonly used as a bulking agent, this is usually of very little concern for the user in terms of desired gains. It is important for any potential user, however, to realize that the rapid gains produced by such strong anabolic steroids as Adrol are often responsible for tendon and connective tissue tears during training as a result of rapid strength gains – Anadrol is often a frequent culprit for such incidences. This is due to the fact that while the muscle itself may increase in mass enough to generate greater force resulting in greater strength, this is not the case for connective tissue and tendons. Connective tissue and tendons strengthen and build at a far slower rate (even in the presence of anabolic steroids) than do muscle tissue. As a result, the strength and force generated by the muscle tissue can tend to breach the capacity that the connective tissue can handle, and the result is torn connective tissue. This is direct evidence that it is possible for individuals to gain too much too fast more than the body can handle (this is especially true for beginners who have not been weight lifting for very long before they make the impatient and hasty decision to use anabolic steroids – to those who fall into this category, be warned).
Although I am usually not inclined to posit speculations on why a particular drug does or doesn't do something, in this case I will. Im guessing that the higher doses of Anadrol cause enough appetite suppression (at least anecdotally) to make eating rather difficult. It can also increase insulin resistance and glucose intolerance (5). This has the effect of making macronutrient absorption more inefficient, and could also be a factor in reducing gains when the dosage goes over 100mgs/day. Unfortunately, Anadrol also has a reasonably profound effect on your body's natural hormonal system, on par with most other oral steroids , but not as bad as most injectables, and its certainly not as harsh on your lipid profile as many anabolics are