Oxymetholone water retention

There is limited information available on the pharmacokinetics of oxymetholone. [4] It appears to be well-absorbed with oral administration . [4] Oxymetholone has very low affinity for human serum sex hormone-binding globulin (SHBG), less than 5% of that of testosterone and less than 1% of that of DHT. [1] The drug is metabolized in the liver by oxidation at the C2 position, reduction at the C3 position, hydroxylation at the C17 position, and conjugation . [4] [2] The C2 hydroxymethylene group of oxymetholone can be cleaved to form mestanolone (17α-methyl-DHT), which may contribute to the effects of oxymetholone. [3] The elimination half-life of oxymetholone is unknown. [2] Oxymetholone and its metabolites are eliminated in the urine . [1] [2]

Anapolon is available in injection form, the dosage of 50 , dosages used from 50 to 200 mg per day. Surprisingly, Anadrol therapeutic dosage much higher and sports is 1-5 mg per kilogram body weight per day! If you follow this recommendation, an athlete weighing 100 kg should take 500 mg of anabolic per day. But many bodybuilders will never accept even the most experienced users. There is some evidence that using a dosage of 300 or more mg/day, far less water is accumulated and the drug shows a strong quality of fat burner. However, such dosage should be treated with caution, and there is a lot of products suitable for cutting.

It is interesting to note that oxymetholone does exhibit some tendency to convert to dihydrotestosterone in the body, although this does not occur via the 5-alpha reductase enzyme. Oxymetholone is already a dihydrotestosterone-based steroid, so no such alteration can take place. Aside from the added c-17 alpha alkylation (discussed below), oxymetholone differs from DHT only by the addition of a 2-hydroxymethylene group. This grouping can be removed metabolically, reducing oxymetholone to the potent androgen 17alpha-methyl dihydrotestosterone (mestanolone). 387 There is little doubt that this biotransformation contributes at least on some level to the androgenic nature of this steroid. Note that since 5-alpha reductase is not involved, the relative androgenicity of oxymetholone is not affected by the concurrent use of finasteride or dutasteride.

Its negative influence may be divided into three major groupings. Side effects in men:

  1. gynecomastia
  2. increased hair loss
  3. body hair growth
  4. a serious increase of cholesterol levels
  5. a suppression of natural testosterone production
Side effects in women:
  1. body hair growth
  2. a deepening of the vocal chords
  3. the abnormally large clitoris
  4. a decrease in breast size
  5. deviations of menstrual cycles
Side effects for both genders:
  1. a severe water retention
  2. irregular blood pressure
  3. acne
  4. an enhancement of liver enzyme values

Oxymetholone water retention

oxymetholone water retention

Its negative influence may be divided into three major groupings. Side effects in men:

  1. gynecomastia
  2. increased hair loss
  3. body hair growth
  4. a serious increase of cholesterol levels
  5. a suppression of natural testosterone production
Side effects in women:
  1. body hair growth
  2. a deepening of the vocal chords
  3. the abnormally large clitoris
  4. a decrease in breast size
  5. deviations of menstrual cycles
Side effects for both genders:
  1. a severe water retention
  2. irregular blood pressure
  3. acne
  4. an enhancement of liver enzyme values

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